hotsync.exe is a process which is deals with the Synchronisation of Palm-based PDAs to your computer. Set to start automatically, this application is always resident by default and should not be disabled where regular use of the PocketPC is concerned.
Non-system processes like hotsync.exe originate from software you installed on your system. Since most applications store data in your system's registry, it is likely that your registry has suffered fragmentation and accumulated invalid entries which can affect your PC's performance. It is recommended that you check your registry to identify slowdown issues