e_s4i2f1.exe is a process which belongs to the EPSON Status Monitor 3 which is installed alongside your Epson printer and offers additional diagnostic and maintenance functions. "This program is a non-essential process, but should not be terminated unless suspected to be causing problems. "
Non-system processes like e_s4i2f1.exe originate from software you installed on your system. Since most applications store data in your system's registry, it is likely that your registry has suffered fragmentation and accumulated invalid entries which can affect your PC's performance. It is recommended that you check your registry to identify slowdown issues